Tests
We process 40m tests per year across a repertoire of over 650 routine and specialist laboratory tests.
Find out about the full A-Z list of tests processed at Sheffield Teaching Hospitals Laboratory Medicine and Sheffield Children’s Hospital
A
Acetycholinesterase Isoenzyme , AChE, NEURONAL AchE
Acetylcholine Receptor Anitbodies, AchR, ACR
Acid Glycoprotein (OROSOMUCOID) / AGP
Activated Partial Thromboplastin Time (APTT)
Activated Protein C Resistance (APCR)
Acute Leukaemia Immunophenotyping
Adalimumab Antibodies / Anti Drug Antibodies (ADA)
Adalimumab Drug Level, Trough Adalimumab, HUMIRA, Anti TNF Alpha
Adrenal Antibodies (see endocrine autoantibodies)
AFP Allotype - Lectin Binding Index, Fucosylation Index, Yolk Sac AFP
Alanine Transaminase (ALT SGPT)
Aldolase B mutation (Hereditary Fructose Intolerance)
ALEX Allergy Chip ( Allergy Explorer )
Alkaline Phosphatase Isoenzymes
Allergen Specific IgG Bee/Wasp Venom
ALPHA - Foetoprotein (AFP) (Tumour Marker)
ALPHA - Foetoprotein, AFP, Amniotic Fluid
ALPHA 1 Antitrypsin PCR Genotype (Anti-Trypsin)
ALPHA 1 Antitrypsin Phenotype, PI Typing (Anti-Trypsin)
ALPHA 1 Microglobulin, ALPHA - 1MG, Protein HC
Alternative Pathway Haemolytic Complement (AP50)
Amiodarone with desethylamiodarone
Amitriptyline and Nortriptyline
Anaesthetic/Drug Adverse Reactions (NARCOS)
ANCA, IIF Screen Anti-Neutrophil Cytoplasmic Antibodies
Angiotensin Converting Enzyme (ACE)
Anti HBs (HBsAb, anti-HBs, Hepatitis B Surface Antibody)
Anti-beta 2 Glycoprotein 1 Antibody (anti-β2 GP1 Ab)
Anti-Cardiolipin Antibody (ACLA)
Anti-Nuclear Antibody (ANA HEP2000) (ANF)
Antidiuretic hormone (Arginine Vasopressin AVP, ADH)
Antithrombin Antigen (ATIIIAg)
Aspartate Aminotransferase (AST, SGOT)
Aspergillus Antigen (Galactomanan)
Assays for Gentamicin, Tobramycin, Vancomycin and Teicoplanin
Atypical Pneumonia Serology ( acute or convalascent )
B
Basophil Activation Test (BAT)
Bence Jones Protein (BJP), Urine Free Light Chains, BJP (24 hour excretion)
Beta 2 Glycoprotein 1 Antibodies IgG and IgM (B2GP)
Beta 2 Interferon Neutralising Antibody
Bile Acids (3a-hydroxy bile acids)
Bilirubin (Total, Conjugated (Direct) )
Blood Film (Peripheral blood morphology)
Bone Alkaline Phosphatase (Bone ALP)
Bordetella pertussis, Whooping Cough, Pernasal Swab
Bordetella Serology: Whooping cough
BRAF, NRAS/BRAF, KRAS, EGFR, MSI and Genefusion Molecular Testing
Bronchial Washings / Broncho Alveolar Lavage (BAL)
C
C1 Esterase Inhibitor (Quantitational and Functional Level)
C3d Levels, C3 Breakdown Product
C5-C9 (C5, C6, C7, C8, C9), Membrane Attack Complex (MAC)
CA15-3, Polymorphous Epithelial Mucin
Caeruloplasmin, Wilsons / Cirrhosis Screen (Copper Oxidase) / Ferroxidase
Calcitonin (Charing Cross Assay, STH requests)
Carbapenemase Producing Enterobacteriaceae (CPE) Gram-Negative Resistance Screening
Carbohydrate Deficient Transferrin (CDT)
Carboxyhaemoglobin / Carbon Monoxide
Carcinoembryonic Antigen (CEA)
Carcinoembryonic Antigen (CEA) in Pancreatic Cyst Fluid
Cardiolipin Antibodies (ACA) IgG and IgM
Carotenoids (alpha-carotene, beta-carotene)
Catecholamines ( Adrenaline, Noradrenaline and Dopamine)
Catheter Tips (CVP, Intravenous, Long Line, Ventricular)
CD11C and CD123 Dentritic Cell Analysis (DCML Screen)
Centromere Antibody, IIF, Kinetechore
Cerebellum (Purkinje) Cell Antibody IIF Screen (Hu, Ri, Yo, Tr, CV2, Ma/Ta), Neuronal Antibody
Chlamydia pneumoniae/psittaci PCR
Chlamydia trachomatis and Gonorrhoea Screening
Classical Pathway Haemolytic Complement Assay (CH50)
Clostridium difficile screen (C.diff)
Clotting Factor Assays (Factors VIII, IX, II, V, VII, X, XI or XII)
Collagen Binding Assay (VWF:CB)
Complement - Factor H / Factor I
Cortisol and cortisone (salivary)
CSF (Meningitis, Encephalitis, Subarachnoid haemorrhage)
CSF TAU Protein (Beta 2 Transferrin) for Rhinorrhoea
Cyclic Citrullinated Peptide (CCP) Antibody
Cyclosporin/Ciclosporin (CYA, CSA)
Cystic Fibrosis Samples, Sputum, Cough Swab, NPA
Cytomegalovirus (CMV) IgG Avidity
Cytomegalovirus IgG Antibody (CMV IgG)
D
Dehydroepiandrosterone Sulphate (DHEAS)
Dental Specimens (Pus, swab of pus)
Dilute Russell's Viper Venom Time (DRVVT)
Diphtheria Antibodies (Functional Antibodies)
Direct Anti-Human Globulin Test (Coombs / DCT / DAT)
Direct Immunofluorescence (DIF)
Direct Thrombin Inhibitor Monitoring
Disseminated Intravascular Coagulation (DIC) Screen
Diuretic screen: Thiazides, Indapamide, Frusemide
DNA Antibodies, Double-Stranded IgG Crithidia Assay
DNA Antibodies, Double-Stranded, IgG dsDNA
E
ENA Antibodies, ENA Specific Types, RO (SS-A)/LA (SS-B) /SM/RNP/SCL-70/JO-1
Endocrine Antibodies (Adrenal, Ovarian, Testes)
Enhanced Liver Fibrosis Test (ELF)
Enterocyte Autoantibodies (EABG) and Goblet Cell Antibodies
Eosinophil Cationic Protein (ECP)
Epstein Barr Virus (EBNA IgG EBV Immunity)
Epstein Barr Virus (EBV) Acute Antibody Screen (EBV IgM)
Epstein Barr Virus (EBV) Immunity Screen (EBV IgG)
Epstein Barr Virus CA IgG (EBV CA IgG) (EB VCA IgG)
Epstein Barr Virus CA IgM (EBVCA IgM) (EB VCA IgM, EBV IgM)
Erlichia Serology (anaplasma phagcytophilum)
Erythrocyte Sedimentation Rate (ESR)
F
Factor IX Gene Mutation Screen
Factor VIII Binding Assay ELISA
Factor VIII Gene Inversion Analysis (IVS1)
Factor VIII Gene Inversion Analysis (IVS22)
Factor VIII Genemutation Screen
Factor VIII Inhibitors (one-stage, chromogenic, porcine)
Faecal Immunochemical Test (FIT)
Familial Hypercholesterolaemia (FH) Genetics
Fibroblast Growth Factor 23 (FGF23)
Fine Needle Aspirate [FNA] Cytology and Systemic Cytology
First Trimester Down's Screening, Combined Test (PAPPA FBHCG) Trisomy 13 and Trisomy 18 Risk Factors
Follicle Stimulating Hormone (FSH)
Free Protein S Antigen (FPSAg)
Full Blood Count including White Cell Differential (FBC)
Further investigation of Antithrombin
G
Galactomannan antigen / Asp Ag
Galactosaemia screen (Galactose -1- phosphate uridyl transferase)
Galactose-1-phosphate, Galactose-1-phosphate uridyl transferase (quantitative) and Galactokinase
Gamma glutamyl transferase (GGT)
Ganglioside Antibodies GD1a, GD1b, GT1b (IgG or IgM)
Ganglioside Antibodies GM1 (IgG or IgM)
Ganglioside Antibodies GQ1b (IgG or IgM)
Gastric Parietal Cell Antibody
GBS Screen, Group B Streptococcus, HSB, Introital Swab
Genital Swab Culture (HVS, Cervical, Vaginal, Urethral, Placental)
Gliadin Antibodies (IgG and IgA)
Glomerular Basement Membrane Antibodies (GBM)
Glucose-6-Phosphate Dehydrogenase ( G6PD )
Glutamic Acid Decarboxylase Antibodies (GAD, GAD65)
Glycosaminoglycans (Mucopolysaccharides, MPS)
H
Haemoglobinopathy/Thalassaemia Screen
Haemophilus Influenzae B (HiB Antibodies, Functional Antibodies)
Helicobacter pylori Faecal Antigen Test
Helicobacter pylori Gastric Biopsy
HEP 2 Antigen Blot (SS-A, SS-B, Sm, RNP, SCL-70, JO-1, PM-SCL, CENT B, CENT C, AMA-M2, RIB-P, RO52)
Heparin Induced Thrombocytopenia ( HIT ) Screen
Hepatitis A IgM ( HAV IgM, Hep A IgM )
Hepatitis A Total Antibody (HAV AB, HAV IgG)
Hepatitis B core Antibody (HBc Ab)
Hepatitis B core IgM (HBc IgM)
Hepatitis B DNA (HBV Viral load, Hepatitis B viral load)
Hepatitis B Surface Antigen (HBsAg, Hep B Screen)
Hepatitis C PCR / HCV Viral Load
Herpes Simplex Type Specific Serology
High Sensitivity C Reactive Protein (hsCRP)
Highly Pathogenic Avian Influenza ( HPAI ) ( Avian Flu ) ( H5N1 )
Histopathology (Surgical Specimens)
HIV oral fluid testing (Ag/Ab) (Oracol swab)
HIV Screen (HIV1 HIV2, HIV Ag/Ab)
HIV Therapeuttic Drug Monitoring
Holotranscobalamin (Active B12)
HSV Immunity (HSV IgG Herpes Simplex Virus Serology)
Human Anti-Mouse Antibodies, HAMA
Human Chorionic Gonadotrophin / LDH
Human Chorionic Gonadotropin (HCG)
I
IA2 Antibodies, Anti Tyrosine Phosphatase Antibodies
IgA Tissue Transglutaminase 6 Antibodies (TTG6, TG6)
IGF Binding Protein 3 ( IGFBP3 )
Immuno Solid-phase Allergen Chip (ISAC)
Immunoglobulin (IgG IgA IgM) Levels with Electrophoresis
Immunoglobulin Heavy Chain Gene Rearrangement (IgH)
Infectious Mononucleosis Screen (Glandular Fever)
Infliximab Antibodies, Anti-Drug Antibodies, ADA
Infliximab Drug Level, Trough Infliximab, ANTI-TNF ALPHA
Insulin-Like Growth Factor (IGF-1)
Insulin-like growth factor II (IGF-II)
Intermediary Metabolites (Free Fatty Acids, 3-hydroxybutyrate)
International Normalised Ratio (INR)
Intra-Operative Frozen Section (Urgent)
Intrinsic Factor Antibody (IFA)
Iron, TIBC, Transferrin Saturation, Iron Profile
J
Japanese B encephalitis Serology
K
L
Legionella Investigations (Legionairres Disease, Atypical pneumonia)
Lipids (Cholesterol, triglycerides, HDL)
Lipoproteins: lipoprotein (a), apolipoprotein (a) or lipoprotein (X)
Liver biopsy for copper or iron quantitation
Liver and Gastric Parietal Cell Antibodies, LKS Substrate ( ANA, AMA, SMA, LKM, GPC )
Liver Blot (AMA-M2, M2-E3, Sp100, PML Ag, gp210, LKM-1, LC-1,SLA/LP, RO52)
Lupus Anticoagulant Antibody Screen
Lyme Disease Serology (Borrelia Serology)
Lymphocyte PHA/OKT3 Response, Lymphocyte Proliferation
Lymphocyte Subsets (HIV Immune Monitoring)
Lymphoproliferative investigation (Peripheral blood lymphocytosis, CLL, Lymphoma)
M
Macro Creatine Kinase (Macro CK)
Malarial Parasites (and other Blood Borne Parasites)
Mannose Binding Lectin (MBL / MBP)
Methicillin Resistant Staphylococcus aureus (MRSA)
Methicillin Sensitive Staphylococcus aureus (MSSA)
Methylmalonate (urine or plasma)
Middle Eastern Respiratory Syndrome PCR (MERS)
Mitochondrial Antibody, PBC Screen (AMA)
Muscle Specific Kinase Antibodies
Mycobacteria ( AAFB, TB Tuberculosis )
Mycology, Fungal Culture of Skin, Hair and Nail (Dermatophytes)
Myelin Associated Glycoprotein Antibodies (ANTI-MAG)
Myelin Oligodendrocyte Glycoprotein Antibodies (MOG Antibodies)
Myelin Sheath / Myelin Associated Glycoprotein by IIF
Myeloperoxidase (MPO) Antibodies
N
N-Methyl-D-Aspartate Receptor Antibodies ( NMDAR )
Neonatal Blood Group including Direct Anti-Human Globulin Test (Coombs)
Neuromyelitis Optica IgG Antibodies/Aquaporin 4 Antibodies/NMO
Neuronal Blot (Amphiphysin, CV2.1, PNMA2 [Ma2/Ta], RI, YO, HU)
Neurone Specific Enolase ( NSE ) Gamma-Enolase
Neurotransmitters (CSF) (monoamine metabolites)
Neutrophil Function : Di-Hydrorhodamine Test ( DHR )
Non-Specific Clotting Factor Inhibitor
Norovirus PCR (Norwalk Like Virus)
O
Oligoclonal Bands, CSF IgG Oligoclonal Bands and IgG/ALB Ratio
One Step Nucleic Acid Amplification (OSNA)
Oxysterol (Neimann-Pick type C)
P
Parathyroid Hormone Related Peptide (PTH rP)
Pemphigoid and Pemphigus Antibodies. Skin Antibodies.
Phospholipase A2 Antibody (PLA2R) Antiphospholipase A2 Antibody MPLA2R
Phytosterols ( inc. sitosterol, campesterol, stigmasterol )
Pituitary polypeptide - alpha subunit
Placental Alkaline Phosphatase (PLAP)
Pneumococcal Antibodies (Functional Antibodies)
PNH Screen and High Resolution Assay
Porphobilinogen (PBG) in Urine: Acute Porphyria
Porphyrin tests: Cutaneous Porphyria
Precipitins, Avian (Budgie, Pigeon)
Precipitins, Farmers Lung / Micropolysporum / Thermoactinomyces
Primary Immunodeficiency (PID) Panel
Procollagen Type III Peptide, P3NP
Protein (urine):- Protein:creatinine ratio (PCR) or 24 hour urine protein
Protein C (PC) Chromogenic Assay
Prothrombin 20210A Allele (PT20210A)
PSA Index (PSA Ratio Free to Bound)
Q
Quantiferon (Gamma Interferon For TB)
R
Renal Biopsy, Immunofluorescent (Native or Transplant Kidney)
Respiratory Sincytial Virus (RSV) Antigen Detection
Rheumatoid Factor Total Antibody (IgM)
RNA Polymerase III Antibodies (RNA Polymerase 3)
Rochilimea Serology (Bartonella)
Rocky Mountain Spotted Fever Serology
Rubella Antibody Screen (Rubella Igg Rubella Immunity)
S
Salivary Duct Antibody and Salivary Gland Antibody
Screen Entire Von Willebrand Factor Gene for Mutations
Screen for Mutation within EXON 28 of VWF
Screen for Mutation within the FVIII Binding Region of VWF (exons 18 - 27)
SCREEN VON WILLEBRANDS DISEASE (VIII:C VWF:Ag VWF:Rcof)
Second Trimester Down's Screening. Quadruple Test (Total HCG, AFP, UE3, INHIBIN A).
Serum Free Light Chains (SFLC)
Sex Hormone Binding Globulin (SHBG)
Skin Antibodies: BP180, BP230, Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3)
Sputum Culture, Induced Sputum
St Louis encephalitis Serology
Sterile Fluid Examination (Joint, Synovial, Drain, Ascitic, CAPD, Pleural)
Streptococcal Serology - ASOT and Anti Dnase B
Swabs (Wound, Ear, Nose, Eye and Throat)
Syphilis Confirmation (VDRL,TPPA)
Syphilis Screen (Trepanemal Screen)
T
T Cell Gene Rearrangements (TCR)
T lymphocytes from CD3 selection
Tetanus Antibodies (Functional Antibodies)
Thioguanine nucleotides/thiopurine metabolites ( 6TGN & 6MMPN )
Thiopurine Methyl Transferase (TPMT)
Thrombin Time and Protamine Thrombin
Thrombophilia and Lupus Screen
Thrombophilia Screen ( excluding Lupus Screen )
Thrombospondin Type-1 Domain containing 7A (THSD7A)
Thyroid Microsomal (Peroxidase) Antibodies, TPO
Thyroid Receptor Antibodies (TSH Receptor Antibodies), TRAb.
Thyroid Stimulating Hormone (TSH)
Ticks, Fleas and Lice ( Ectoparasites )
Tissue and Biopsies for Culture
Tissue Culture and Enzyme Assay
Tissue Transglutaminase Antibody (TTG) (IgG and IgA)
Total Plasma Homocysteine (tHCy)
Total Procollagen Type-1 N-Terminal Propeptide/Procollagen Extension Peptide (P1NP)
Toxicology / Drug Screen in Suspected Poisoning
Toxoplasma antibody screening test (Toxoplasma Serology)
Toxoplasma Confirmation (Toxoplasma IgG , Toxoplasma IgM)
Transferrin Glycoforms ( isoelectric focusing )
Trichomonas vaginalis (TV) TMA screening
Trimethylamine and Oxide (Fish Odour Syndrome)
Two-Stage Clotting Factor VIII:C
U
Urine Gluten Immunogenic Peptides
Urine Microscopy and Culture (MSU,CSU,SPA,CCU)
Urine Protein Selectivity / Clearance Profile ( IgG / Albumin Ratio ) / Protein Clearance Ratio
V
Vancomycin (Glycopeptide) Resistant Enterococci (VRE)
Varicella Zoaster IgG confirmation (VZV IgG confirmation)
Varicella Zoster IgG (VZV IgG)
Vasculitic Screen (C3, C4, Immunoglobulins, ANCA, Hep2 ( ANA ), RF)
Very Long Chain Fatty Acids (VLCFA)
Viral Hepatitis Assess vaccine need (ICE)
Viral Hepatitis Assess vaccine response (ICE)
Viral Hepatitis New Hep B referral (ICE)
Viral Hepatitis Past infections screen (ICE)
Viral Hepatitis Screening tests (ICE)
Vitamin B6 ( Pyridoxine - Pyridoxal phosphate and isomers )
Vitamin C (Plasma Ascorbic acid)
Voltage-Gated Calcium Channel Antibodies
Voltage-Gated Potassium Channel Antibodies
von Willebrand Factor (VWF) Multimers
W
White cell or leucocyte cystine - SEE Leukocyte Cysteine
Y
Z
1
1, 25 Di-Hydroxy Vitamin D ( Active 1,25 Vitamin D )
25-Hydroxy Vitamin D (Vitamin D)
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